2-ETHYLHEXYL CHLOROFORMATE

PRODUCT IDENTIFICATION

24468-13-1

ClCO₂CH(CH₂H₅)(CH₂)₃CH₃

192.68

H.S. CODE

TOXICITY

C([C@@H](CC)CCCC)OC(Cl)=O

CLASSIFICATION

EXTRA NOTES

PHYSICAL AND CHEMICAL PROPERTIES

clear liquid

-50 C

hydrolysis

REFRACTIVE INDEX

Stable under ordinary conditions

EXTERNAL LINKS & GENERAL DESCRIPTION

Wikipedia Linking - Chloroformate

Google Scholar Search

Drug Information Portal (U.S. National Library of Medicine) - 2-Ethylhexyl chloroformate

PubChem Compound Summary - 2-Ethylhexyl chloroformate

http://www.ebi.ac.uk/ -  2-Ethylhexyl chloroformate

http://www.ncbi.nlm.nih.gov/ -  2-Ethylhexyl chloroformate

Local:
Phosgene (carbonyl dichloride, COCl₂) is a very reactive chemical intermediate to prepare isocyanates, chloroformates, isothiocyanates, isonitriles and acid chlorides as well as in the production of polymers including polyurethanes, polycarbonates, and polyureas. Phosgene , however, is extremely toxic gas associated strong safety hazards and handling precautions. It is listed on schedule 3 of the Chemical Weapons Convention. All production sites must be declared to the OPCW. Phosgene is almost entirely in captive consume in the production plant. Chloroformates are relatively less dangerous route to prepare important families of compounds, the carbonates and carbamates. Carbonates are prepared by reaction with alcohol (or phenol) and carbamates are by reaction with an amine ( primary or secondary). Chloroformates are starting materials to prepare carbonate and carbamate derivatives that are used in the pharmaceutical and agrochemical industry.

Chloroformates are used as an intermediate for the synthesis of pharmaceuticals and agrochemicals especially for some carbamates (salt or ester of an amide of carbonic acid) which are used as insecticides, fungicides, herbicides, sprout inhibitors and biocides. They are used in the production of urethane and organic peroxides. Peptide grade is used to block the amino group in peptide synthesis.

APPEARANCE

clear liquid

99.0% min

COLOR, APHA

20 max

HCl

0.05% max

PHOSGENE

0.1% max

IRON

1ppm max

CARBONATE

0.5% max

ALCOHOL

0.5% max

HAZARD OVERVIEW

Combustible Liquid, Lachrymator.

GHS

PICTOGRAMS

HAZARD STATEMENTS

H301 + H311 + H331-H314

P STATEMENTS

P261-P280-P301 + P310-P305 + P351 + P338-P310

RISK PHRASES

23/24/25-34

SAFETY PHRASES

26-27-36/37/39-45